How AB SCIEX 4500 Series Works with Different Instruments

 How AB SCIEX 4500 Series Works with Different Instruments

Hardware Profiles

A hardware profile tells the Sciex 4500 how the mass spectrometer and the devices are configured and connected to the computer. Multiple hardware profiles can be set up, but only one profile can be active at any time.

When a hardware profile is created in the Hardware Configuration Editor, the peripheral devices must be configured so that the system can communicate with them. Configuring the peripheral devices requires two methods: setting up the physical connections and configuring the software to communicate with the peripheral devices. When the software is installed, the driver needed for each peripheral device is installed after the peripheral devices are connected to the computer and set up the appropriate Sciex 4500 configuration information.

Each hardware profile must associate a mass spectrometer. Before creating any ideological method, ensure that all devices used in the process are included in the hardware profile, including the syringe pump. The equipment configured in the active hardware setting and selected in the Add/Remove Device Method dialogue shown as icons in the Acquisition method pane. Only peripheral equipment included in the active hardware profile can be used when creating acquisition methods.

Each hardware profile must have a mass spectrometer. Before using an acquisition method, ensure that all devices used in the process are included in the hardware profile. The devices engraved in the active hardware profile and selected in the Remove Device Method dialogue are shown as icons in the needed method pane. Only peripheral devices included in the functional hardware can be used when creating acquisition methods.

Operational Provision and Impediment

Work in a well-ventilated area.

  • Always use assigned personal protective devices, including powder-free neoprene or nitrile gloves, glasses, and a lab coat.
  • Avoid firing sources when working with flammable materials, such as isopropanol, methanol, and other volatile solvents.
  • Take care in use and discard any chemicals. The risk of personal injury if the proper process for handling and disposing of chemicals are not followed.
  • Avoid contact with chemicals during cleaning and proper wash hands after use.
  • Make sure that all exhaust parts are connected correctly and that all connections are functioning as designed. • Collect all spent liquids and dispose of them as hazardous waste.
  • Comply with all local rules for the storage, handling, and disposal of hazardous, toxic, or radioactive materials.
  • (Recommended) Use secondary containment trays beneath the roughing pump, the solvent bottles, and the waste collection container to capture potential chemical spills.

Trained Personnel

Only equipped SCIEX personnel shall be placed, inspect, and service the equipment. After installing the system, the Field Service personnel uses the Customer Familiarization Checklist to orient the customer on system operation, cleaning, and essential conserve.

Only personnel qualified by the manufacturer shall preserve the equipment. A lab designate can be familiarized with the Qualified Maintenance Person procedures during the installation. A QMP is a person who is suitably aware of the electrical and chemical risks associated with servicing laboratory equipment. Laboratory Conditions Operating Conditions

The system is equipped to operate safely under this situation.

  • Indoors
  • Altitude: Up to 2 000 m (6 300 feet) above sea level
  • Ambient temperature: 4 °C (41 °F) to 40 °C (104 °F)
  • Relative humidity: 90% for temperatures up to 31 °C (88 °F), decreasing linearly to 40% at 50 °C (104 °F)
  • Mains supply voltage fluctuations: ±11% of the nominal voltage
  • Impairment overvoltage: Up to the levels of Overvoltage level III
  • Temporary overvoltage on the mains supply
  • Pollution degree: Pollution Degree 3 Performance Specifications The system is designed to meet specifications under these conditions:
  • Ambient temperature: 15 °C (59 °F) to 30 °C (86 °F) Over time, the temperature must remain within a range of 4 °C (6.2 °F), with the rate of the temperature change not exceeding 2 °C (5.6 °F) per hour. Ambient temperature fluctuations exceeding the limits might result in mass move in spectra.
  • Relative humidity: 20% to 80%, non-condensing

Dom Charlie

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